Hodgkin’s Lymphoma
Introduction to Hodgkin’s lymphoma
Welcome to the Hodgkin’s lymphoma subsection of the Haematology for the MSRA course.
This section is designed to provide comprehensive and structured learning materials to help you understand and master the topic of Hodgkin’s lymphoma for the MSRA.
Resources for Hodgkin’s lymphoma:
- Hodgkin’s lymphoma Revision Notes for MSRA: Detailed and concise traditional revision notes covering all essential aspects of Hodgkin’s lymphoma, including its causes, symptoms, diagnosis, and treatment. These notes are designed using UK NICE guidelines. Use the notes to gain an initial understanding of the topic.
- Hodgkin’s lymphoma Flashcards for MSRA: Interactive flashcards to help you memorise key facts and concepts about Hodgkin’s lymphoma. These are perfect for quick reviews and reinforcing your knowledge.
- Hodgkin’s lymphoma Accordion Q&A Notes for the MSRA: A unique feature where you can test your understanding of Hodgkin’s lymphoma with question-and-answer style revision notes. This format helps in active learning and retention of important information.
- Hodgkin’s lymphoma Rapid Fire Quiz for MSRA: A short quiz to test your knowledge and recall of Hodgkin’s lymphoma-related concepts. This is an excellent way to assess your progress and identify areas that need further review.
We hope you find these resources helpful and engaging as you prepare for the MSRA.
Key Points about Hodgkin’s lymphoma
- Definition: Hodgkin’s lymphoma is a type of lymphatic cancer characterised by the presence of Reed-Sternberg cells, affecting lymph nodes and potentially spreading to other organs.
- Causes:
- Unknown exact cause but associated with:
- Epstein-Barr virus (EBV) infection.
- Family history of lymphoma.
- Immunosuppression.
- Symptoms:
- Painless lymphadenopathy (usually in the neck, armpits, or groin).
- Systemic “B symptoms”: fever, night sweats, and weight loss.
- Fatigue and pruritus.
- Investigations:
- Lymph node biopsy showing Reed-Sternberg cells.
- Blood tests (full blood count, LDH levels).
- Imaging: PET-CT scan for staging and treatment response evaluation.
- Management:
- Chemotherapy (ABVD regimen: Adriamycin, Bleomycin, Vinblastine, Dacarbazine).
- Radiotherapy for early-stage disease.
- Stem cell transplant in relapsed or refractory cases.
- Complications:
- Long-term risk of secondary cancers (e.g., breast or lung cancer).
- Cardiac and pulmonary toxicity from chemotherapy.
- Fertility issues due to treatment.
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