Small-Cell Lung Cancer

A 70-year-old woman is diagnosed with limited-stage small-cell lung cancer (SCLC) following a biopsy of a left hilar mass. Staging with PET-CT shows that the cancer is confined to the left hemithorax and mediastinal lymph nodes, without distant metastasis. Her performance status is good, and she has no significant comorbidities.

What is the most appropriate initial treatment for this patient?

A 68-year-old man with extensive-stage small-cell lung cancer (SCLC) presents with new-onset headache, confusion, and seizures. He has a known history of brain metastases. On examination, he has altered mental status and focal neurological deficits. An urgent brain MRI shows multiple enhancing lesions with significant surrounding edema.

What is the most appropriate immediate management for his current symptoms?

A 55-year-old man presents with persistent cough and weight loss. Imaging reveals a mass in the lung, and biopsy confirms small cell lung cancer (SCLC).

Which of the following characteristics is most associated with small cell lung cancer (SCLC)?

A 58-year-old man is diagnosed with limited-stage small cell lung cancer (SCLC) confined to the left lung and mediastinal lymph nodes. He has no significant comorbidities and is in good overall health.

What is the most appropriate initial treatment for limited-stage small cell lung cancer?

A 62-year-old man with a 50-pack-year smoking history presents with a 2-month history of worsening cough, weight loss, and dyspnoea. He also reports chest pain and hemoptysis. On examination, he has a respiratory rate of 22 breaths/min, and decreased breath sounds with dullness to percussion over the right lung base. A chest X-ray reveals a right hilar mass with associated pleural effusion.

What is the most appropriate initial diagnostic test to confirm small-cell lung cancer?